This site is mainly aimed at teachers and students at Key Stage 4 and in post-16 education. It is specifically aimed to support applied science courses and parts of the statutory work-related learning framework.
It gives a context for how Key Skills and Science are used in the pharmaceutical industry.
For work-related learning background see the QCA website
For details of the frameworks for work-related learning see the relevant section of the QCA website
Mapping of the modules to the work-related framework and other parts of the curriculum is shown below.
Module
Lab & Pilot Plant Tours
Tours aimed at post-16 chemistry courses.
- Virtual tours of laboratories and pilot plants show how chemistry is carried out safely in an industrial workplace setting.
This module is linked to these elements:
- Framework element 6 - Students undertake tasks and activities set in work contexts.
- Framework element 7 - Students learn from contact with personnel from different employment sectors.
- Framework element 8 - Students have experience (direct or indirect) of working practices and environments.
Applied Science: Double Award
2.3.3 Chemical Manufacture
- State that some chemicals are produced in a very small scale in the chemical industry and are called fine or speciality chemicals
- Recall that medicines ... are examples of fine or speciality chemicals
-
13.6 Assessment Evidence for Unit 4: Using Scientific Skills for the Benefit of Society
- A report on the production of a chemical product
AP4.1 The Chemical Industry
- (9) Understand that new chemical products are the result of an extensive programme of research and development (for example new medical drugs)
C7.5 Green Chemistry: The chemical industry
- (2) Recall examples of chemicals ... made on a small scale (drugs)
- (4) Understand that new chemical products ... are the result of an extensive programme of research and development
C4 Chemical Economics
- Compare the relatively small scale production of pharmaceutical drugs to the large scale production of ammonia
C4 Chemical Economics
- Compare the relatively small scale production of pharmaceutical drugs to the large scale production of ammonia
Standard Grade: Social & Vocational Skills
3.2.2 Work
Topics relevant to this module:
- Surveying the job market: ... commerce, opportunities, qualifications
- Choosing a job: kind of jobs, what to look for, weighing up prospects
Relevant Units:
- Personal Development: Self and Work
Chemistry
3.2.11 Analytical Techniques
- Mass spectrometry
- Infrared spectroscopy
3.4.11 Structure determination
- Mass spectrometry
- Infrared spectroscopy
- Nuclear magnetic resonance spectroscopy
Unit 1 Investigating science at work
10.3 You will need to know, understand and be able to demonstrate relevant knowledge of the following:
- the types of organisation which use science;
- how science is used in organisations;
- how health and safety regulations are used in the workplace;
- how the organisation impacts on the local community.
Chemistry
Chemistry (Nuffield)
1.5 The role of instrumentation in analytical chemistry is illustrated by mass spectrometry.
1.7 The introduction to organic chemistry shows how chemists work safely with potentially hazardous chemicals by managing risks.
2.12 Mass spectra and IR
4.9 Spectroscopy and chromatography
Chemistry (Nuffield)
Unit 6 Applying chemistry
- Topic 21 Instrumental methods
Special study: Chemical Engineering
Chemistry A
Chemistry B (Salters)
Science (AS)
2.2 Module 2 Alcohols, halagenoalkanes and analysis
-
2.2.3 Modern Analytical Techniques
infrared spectroscopy;
mass spectrometry.
4.3 Module 3 Analysis
-
4.3.1 Chromatography
thin-layer and gas chromatography;
GC-MS. -
4.3.2 Spectroscopy
NMR spectroscopy;
combined techniques.
How science works
4.2.2.a Analysis of pharmaceuticals
4.2.3.c-f Requirement for chiral drugs and medicines
to minimise side effects, for economical reasons and
to reduce risk to companies from litigation
4.3.1.h,i Use of GC-MS by society in modern analysis
4.2.2.a Analysis of pharmaceuticals
4.2.3.c-f Requirement for chiral drugs and medicines
to minimise side effects, for economical reasons and
to reduce risk to companies from litigation
4.3.1.h,i Use of GC-MS by society in modern analysis
Chemistry B (Salters)
Module F334 Chemistry of Materials
What's in a Medicine?
- Medicine manufacture and testing
- IR spectroscopy and mass spectroscopy
How science works
ix. the benefits and risks of testing medicines;
x. the ethical issues involved in the testing of medicines;
xi. making new compounds and testing for medicinal effect;
ix. the benefits and risks of testing medicines;
x. the ethical issues involved in the testing of medicines;
xi. making new compounds and testing for medicinal effect;
Module F335 Chemistry by Design
Medicines by Design
- Computer modelling and design of drugs
- Synthesis of organic molecules
- NMR spectroscopy
- Using spectroscopic techniques to elucidate structure
How science works
v analyse data from IR, NMR and mass spectra
x, xi drug testing
xi making new compounds and testing for medicinal effect
v analyse data from IR, NMR and mass spectra
x, xi drug testing
xi making new compounds and testing for medicinal effect
Science (AS)
3.3. practical skills in science
-
Case study
Use secondary and/or primary sources to investigate a specific area of scientific research or study.
Chemistry
Unit 3: Chemical reactions
-
The chemical industry
The UK chemical industry is a major contributor to both the quality of our life and our
national economy.
Stages in the manufacture of a new product can include research, pilot study, scaling-up,
production and review.
A chemical manufacturing process usually involves a sequence of steps.
Chemical manufacturing may be organised as a batch or as a continuous process.
Process conditions are chosen to maximise economic efficiency.
Manufacturing costs include capital costs, fixed costs and variable costs.
Safety and environmental issues are of major importance to the chemical industry.
The efficient use of energy is significant in most chemical processes.
Chemistry
Structural analysis
- Mass spectrometry can be used to determine the accurate molecular mass and structural features of an organic compound.
- Infra-red spectroscopy can be used to identify certain functional groups in an organic compound.
-
Nuclear magnetic resonance spectroscopy (nmr) can give information about
1. the different environments of hydrogen atoms in an organic molecule
2. how many hydrogen atoms there are in each of these environments.
Medicines
- Drugs are substances which alter the biochemical processes in the body and those which have a beneficial effect are called medicines.